8:00 |
SESSION IX: NEW APPROACHES & ERADICATION TRIALS - Part I
Chairs: Alain Lafeuillade (General Hospital, Toulon, France), Jean Michel Molina (Hopital Saint Louis, Paris, France)
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| 8:00 |
Designing Clinical Trials for HIV-1 Eradication
Daniel Kuritzkes (Harvard Medical School, Cambridge, USA)
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| 8:20 |
The Role of Chemokines in the Establishment of HIV Latency
Sharon Lewin
|
| 8:40 |
The HIV-1 Eradication Pipeline: Challenges and Opportunities
Daria Hazuda (Merck Research Laboratories, West Point, USA)
|
| 9:00 |
The Effect of Vorinostat on Latent HIV-1 Expression in vivo: Preliminary Findings from a
Clinical Study in ART-suppressed HIV-1-infected Patients
David Margolis (Institute for Global Health & Infectious Diseases, UNC Chapel Hill, Chapel Hill, USA)
|
| 9:20 |
Effect of Maraviroc Intensification on the Decay of HIV-1 DNA in PBMC of Recently Infected
Patients Initiating Treatment with Raltegravir plus Tenofovir/Emtricitabine: a 48-week Randomized Study
Maria Puertas (IrsiCaixa - AIDS Research Institute, Badalona, Spain)
|
| 9:35 |
Dynamics of Immune Activation and PD-1 Expression in Recently Infected HIV-1 Naïve Subjects
Intensifying with Maraviroc a Raltegravir plus Tenofovir/Emtricitabine Regimen
Marta Massanella (IrsiCaixa, Badalona, Spain)
|
| 9:50 |
Picomolar Dichotomous Activity of Gnidimacrin Against HIV-1 Latent Infection
Chin Ho Chen (Duke University Medical Center, Durham, USA)
|
| 10:05 |
Poster Viewing Session |
| 10:30 |
SESSION X: NEW APPROACHES & ERADICATION TRIALS - Part 2
Chairs: David Margolis (Institute for Global Health & Infectious Diseases, UNC Chapel Hill, Chapel Hill, USA), José Gatell (Hospital Clinic, Barcelona, Spain)
|
| 10:30 |
CCR5 Knock-out in Hematopoietic Stem Cells
Paula Cannon (USC Keck School of Medicine, Los Angeles, USA) |
| 10:50 |
A Single Infusion of Zinc Finger Nuclease (ZFN) CCR5 Modified Autologous CD4 T-cells
Correlates with Increases CD4 Counts and Effects on Viral Load in Aviremic HIV-infected Subjects
Carl June (Abramson Cancer Center, University of Pennsylvania, Philadelphia, USA)
|
| 11:10 |
Targeted Disruption of CXCR4 in Human CD4+ T cells with Zinc-finger Nucleases
Craig Wilen (University of Pennsylvania, Philadelphia, USA)
|
| 11:30 |
Excision of HIV Proviral DNA using Tre-recombinase
Jan van Lunzen (University Medical Center Hamburg-Eppendorf, Hamburg, Germany)
|
| 11:45 |
Direct Targeting of Integrated HIV Sequences Using Engineered Homing EndonucleasesExcision of HIV Proviral DNA using Tre-recombinase
Keith Jerome (Fred Hutchinson Cancer Research Center, Seattle, USA)
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12:00 |
Workshop Conclusions
Alain Lafeuillade (General Hospital, Toulon, France), Fraçoise Barré-Sinoussi (Institut Pasteur, Paris, France)
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