MORNING SESSIONS |
8:00 |
SESSION IV: INNATE IMMUNITY AND HIV PERSISTENCE
Chairs: Monsef Benkirane (Laboratory of Molecular Biology, CNRS UPR 1142, Montpellier, France), Marie-Lise Gougeon (Institut Pasteur, Paris, France)
|
| 8:00 |
The Cytosolic Exonuclease TREX1 Digests HIV Reverse Transcripts to Avoid Triggering an Antiviral
Interferon Response in T Cells and Macrophages
Judy Lieberman (Harvard Medical School, Boston, USA) |
| 8:20 |
Innate Immunity & Establishment of HIV Reservoirs
Nicolas Manel (Institut Curie, Paris, France)
|
| 8:40 |
How Samhd1 May Change Our View of Viral Restriction
Nadine Laguette (Laboratory of Molecular Biology, CNRS UPR 1142, Montpellier, France)
|
| 9:00 |
microRNAs and the Innate Immune Response to SIV Infection
Jeanne Sisk (Johns Hopkins University School of Medicine, Baltimore, USA)
|
9:15 |
Break |
| 9:30 |
Poster Viewing Session |
10:00 |
SESSION V: IMMUNE CONTROL OF HIV RESERVOIRS
Chairs: Nicolas Chomont (VGTI-Florida, Port St. Lucie, USA), Sharon Lewin (Burnet Institute, Melbourne, Victoria, Australia) |
| 10:00 |
Relevance of Monitoring HIV Viral DNA Intermediates in vivo
Una O'Doherty (University of Pennsylvania, Philadelphia, USA) |
| 10:20 |
The Impact of HIV-associated Inflammation on HIV Persistence
Steven Deeks (San Francisco General Hospital, University of California, San Francisco)
|
| 10:40 |
Immunological Mechanisms Involved in HIV Persistence
Nicolas Chomont (Vaccine and Gene Therapy Institute of Florida, Port St. Lucie, USA)
|
| 11:00 |
Increased Susceptibility to CD8 T Cell Mediated Killing Limits the HIV-1 Reservoir in
Naïve CD4 T Cells from Elite Controllers
Mathias Lichterfeld (Massachusetts General Hospital, Boston, USA)
|
| 11:15 |
Differential Impact of IL-7 and IL-15 on HIV Reservoir Persistence
Claire Vandergeeten (VGTI-Florida, Port St. Lucie, USA)
|
| 11:30 |
Modulation of Oxidative Stress Induces Apoptosis in Long-lived Phenotypes ex vivo
Barbara Chirullo (ZZItalian Institute of Health, Rome, Italy)
|
| 11:45 |
Lunch |
AFTERNOON SESSIONS |
| 14:00-15:00 |
Poster Viewing Session |
| 14:45-15:30 |
SESSION VI A: LATE BREAKER ABSTRACTS
Chair: Alain Lafeuillade (General Hospital, Toulon, France) |
| 14:45 |
Impact of TLR Ligands Mediated IL-10 Production on HIV Persistence
Rafick Sekaly (VGTI-FL, Port St Lucie, USA) |
| 14:55 |
Plasma Viremia and Cellular HIV-1 DNA Persist Despite Autologous Hematopoietic Stem Cell Transplantation for AIDS-Related Lymphoma
John Mellors (University of Pittsburgh, Pittsburgh, USA) |
| 15:05 |
High Resolution Deep Sequencing Analysis of Viral Persistence and Activation during Natural History of HIV-1 Infection
Maureen Goodenow (University of Florida, Gainsville, USA) |
| 15:15 |
Maraviroc (MRV) can activate NFkB in patients infected with R5 or D/M HIV-1
Santiago Moreno (Hospital Ramon Y Cajal, Madrid, Spain) |
| 15:30-16:00 |
SESSION VI B: RESEARCH PRESENTATIONS FROM FIRMS SUPPORTING THE MEETING
Chair: Alain Lafeuillade (General Hospital, Toulon, France) |
| 15:30 |
Title TBA
On behalf of Gilead Sciences Inc.: Romas Geleziunas (Foster City, USA) |
| 15:45 |
Title TBA
On behalf of Tibotec: Guenter Kraus (Mechelen, Belgium) |
| 16:00 |
SESSION VII: ACUTE HIV INFECTION
Chairs: Mark Wainberg (McGill University AIDS Centre, Montreal, Canada), Martin Markowitz (Aaron Diamond AIDS Research Center, New York, NY, USA) |
| 16:00 |
A Randomized, Open-label Trial of 5-drug Versus Standard 3-drug Pi-based cART Initiated During Acute and Early Infection: 96-week Results
Martin Markowitz (Aaron Diamond AIDS Research Center, New York, NY, USA) |
| 16:20 |
Mega-HAART at Acute HIV Infection
Jintanat Ananworanich (The Thai Red Cross AIDS Research Center, Bangkok, Thailand, and the US Military HIV Research Program, Rockville, USA) |
| 16:40 |
Reduced HIV-1 Reservoir Size after 10 years of Suppressive Antiretroviral Therapy in
Patients Initiating Treatment during Primary Infection
Maria Buzon (Ragon Institute of MGH, MIT and Harvard, Charlestown, USA) |
| 16:55 |
Control of HIV-1 Replication in CD4+ T Lymphocytes by using PKC Theta Inhibitors as a Strategy to Reduce
the Size of Reservoirs during Primary Infection
Mayte Coiras (Instituto de Salud Carlos III, Madrid, Spain) |
| 17:30-19:00 |
SESSION VIII: ANATOMIC RESERVOIRS
Chairs: José Gatell (Hospital Clinic, Barcelona, Spain), Alain Lafeuillade (General Hospital, Toulon, France) |
|
Tissue Analysis of Lymphatic Reservoirs of HIV Infection
Timothy Schaker (Department of Medicine, University of Minnesota, Minneapolis, USA) |
| 17:20 |
Virologic Analysis of Lymphatic Reservoirs of HIV Infection
Mario Stevenson (University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA) |
| 17:40 |
Pharmacologic Analysis of Lymphatic Reservoirs of HIV Infection
Courtney Fletcher (University of Nebraska Medical Center, Omaha, USA) |
| 18:00 |
The Brain and Spleen are Reservoirs of SIV Infection in Macrophages
Janice Clements (Johns Hopkins Univ. School of Medicine, Baltimore, USA) |
| 18:20 |
Poster Viewing Session |
| 20:00 |
Gala Dinner |
