MORNING SESSIONS |
8:00 |
Opening Remarks
Mario Stevenson (University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA)
|
8:10 |
SESSION I: MODELS of HIV PERSISTENCE
Chairs: José Alcami (Instituto de Salud Carlos III, Madrid, Spain),
Monsef Benkirane (Laboratory of Molecular Biology, CNRS UPR 1142, Montpellier, France)
|
| 8:10 |
Viral Reservoirs & Reactivation/Eradication Strategies in SHIV-infected Macaques
Paul Luciw (University of California Davis, Davis, USA) |
| 8:30 |
Simian Models of Viral Persistence
Jeff Lifson (NCI-Frederick, Frederick, USA) |
| 8:50 |
Eradication trials in SIVmac251-infected macaques
Andrea Savarino (Istituto Superiore di Sanità, Rome, Italy)
|
| 9:10 |
HIV-1 Latency in in-vitro Differentiated Central Memory Cells
Vicente Planelles (University of Utah School of Medicine, Salt Lake City, USA)
|
| 9:25 |
Generation of HIV Latency in BLT Humanized Mice
J. Victor Garcia (University of North Carolina at Chapel Hill, Chapel Hill, USA)
|
| 9:40 |
The Contribution of Splenic Macrophages to SIV Infection and Changes in this Population 05
Following Antiretroviral Treatment
Julia Russell (Johns Hopkins University School of Medicine, Baltimore, USA)
|
| 9:55 |
Mega-ART Induces Viral Suppression and Restriction of the Viral Reservoir in a Simian AIDS Model
Iart Shytaj (Istituto Superiore di Sanità, Rome, Italy)
|
| 10:10 |
SIV/Macaque Model of Highly Active Antiretroviral Therapy: Viral Persistence and 07
Ongoing CNS Inflammation
M. Christine Zink (Johns Hopkins University School of Medicine, Baltimore, USA)
|
10:25 |
Break |
| 11:00 |
SESSION II: BASIC SCIENCE OF HIV PERSISTENCE
Chairs: Mario Stevenson (University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA), Alain Lafeuillade (General Hospital, Toulon, France) |
| 11:00 |
Control of HIV Latency by the "Two Peas in a Pod:" Polycomb and P-TEFb
Jonathan Karn (Case Western Reserve University, Cleveland, USA) |
| 11:20 |
New Mechanisms of HIV Transcriptional Latency
Monsef Benkirane (Laboratory of Molecular Biology, CNRS UPR 1142, Montpellier, France)
|
| 11:40 |
Intracellular Tat Expression Modifies the Environment of Infected Lymphocytes
José Alcami (Instituto de Salud Carlos III, Madrid, Spain)
|
| 12:00 |
Thoughts on Elimination of Latent HIV Reservoirs
Jerome Zack (University of California, Los Angeles, USA)
|
| 12:15 |
Lunch |
AFTERNOON SESSIONS |
| 14:00-16:00 |
Poster Viewing Session |
| 16:00 |
SESSION III: VIROLOGICAL ASPECTS OF HIV PERSISTENCE
Chairs: John Coffin (Tufts University, Boston, USA), Christine Rouzioux (CHU Necker-Enfants Malades, Paris, France) |
| 16:00 |
Characterizing Latent HIV Reservoirs
Sarah Palmer (Swedish Institute for Infectious Disease Control and Karolinska Institute, Stockholm, Sweden) |
| 16:20 |
Perspectives on Therapeutic Intervention and Eradication in HIV Infection
Tae-Wook Chun (NIH, Bethesda, USA)
|
| 16:40 |
Residual HIV Replication on ART
Javier Martinez-Picado (AIDS Research Institute (IrsiCaixa) and ICREA, Barcelona, Spain)
|
| 17:00 |
Epigenetic Modifications that Control Latency in T-Cells and Macrophages: Effect Of Chromatin
Remodeling Complexes and Tat Modifications.
Fatah Kashanchi (GMU, Manassas, USA)
|
| 17:15 |
Exosomes from HIV-1 Infected Cells: Trojan Horses that Contain TAR miRNA and Proteins
that Effect Latency
Fatah Kashanchi (GMU, Manassas, USA)
|
| 17:30 |
Targeted Activation of Viral Gene Expression by Exogenous Tat During Infection Inhibits the
Establishment of HIV-1 Latency
Daniel Donahue (McGill University AIDS Centre, Jewish General Hospital, Montreal, Canada)
|
| 17:45 |
M1 Polarization of Human Monocyte-derived Macrophages (MDM) Restricts Pre- and Post-integration Steps
of the HIV-1 Life Cycle. A Potential Role of APOBEC3A
Guido Poli (San Raffaele Scientific Institute & Vita-Salute San Raffaele University, Milano, Italy)
|
| 18:00 |
Hematopoietic Progenitor Cells (HPCs) are Preferentially Infected by CXCR4- and Dual-tropic HIV,
and HIV from Latently Infected HPCs can be Transferred to CD4+ T Cells in vitro
Adewunmi Onafuwa-Nuga (University of Michigan, Ann Abor, USA)
|
| 18:15 |
TRIM22 Inhibits Sp1-dependent HIV-1 Transcription
Elisa Vicenzi (San Raffaele, Milan, Italy)
|
| 19:30 |
Dinner |
