8:00-10:00 AM – SESSION 4: IMMUNOLOGY OF HIV PERSISTENCE
Chairs:
Lydie TRAUTMANN, Associate Professor, OHSU, Vaccine & Gene Therapy Institute, Beaverton – USA
Brad JONES,Assistant Professor, Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Columbia, WA – USA
OP 4.0 T Cells and The Cure Agenda
Bruce WALKER, Founding Director of the Ragon Institute of MGH, MIT and Harvard and the Director of the Harvard University Center for AIDS Research, Cambridge, MA – USA
OP 4.1 HIV persistence during ART: Keeping memory, keeping HIV
Nicolas CHOMONT, Associate Professor in the Department of Microbiology and Immunology at the Université de Montréal – CHUM Research Center, Montreal – CAN
OP 4.2 : Characterizing “exceptional” control among HIV elite controllers
Author(s): M. Peluso 1,*, P. Burbelo 2, S. Kumar 1, S. Munter 1, R. Hoh 1, S. Lee 1, P. Hunt 1, R. Rutishauser 1, T. Henrich 1, S. Deeks 1
1 University of California, San Francisco – San Francisco (USA)
2 National Institutes of Health – Bethesda (USA)
OP 4.3 : Single-cell TCR sequencing reveals that clonally expanded cells highly contribute
to the inducible HIV reservoir during ART
Author(s): P. Gantner 1,*, A. Pagliuzza 2, M. Pardons 1, M. Ramgopal 3, J.P. Routy 3, R. Fromentin 2, N. Chomont 1
1 Université de Montréal – Montréal (CAN)
2 CRCHUM – Montréal (CAN), 3Midway Immunology & Research Center – Fort Pierce (USA)
OP 4.4 : Single-cell phenotyping of HIV-infected expanded clones in ART-suppressed individuals
Author(s): C. Dufour 1,*, M. Pardons 1, R. Fromentin 1, M. Massanella 1, S. Palmer 2, S. Deeks 3, B. Murrell 4, J.P. Routy 5, N. Chomont 1
1 Centre de Recherche du CHUM and Department of Microbiology, Infectiology and Immunology, Université de Montréal – Montreal (CAN)
2 Centre for Virus Research, The Westmead Institute of Medical Research, The University of Sydney – Sydney (AUS)
3 Department of Medicine, University of California San Francisco – California (USA)
4 Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet – Stockholm (SWE)
5 Division of Hematology & Chronic Viral Illness Service, McGill University Heath Centre – Montreal (CAN)
OP 4.5 : The IciStem consortium: T-cell immunology in HIV-1 infected individuals after
allogeneic stem cell transplantation
Author(s): J. Martinez-Picado 3,*, J. Eberhard 1,*, M. Angin 2, C. Passaes 2, M. Salgado 3, J.L. Díez Martín 4, M. Nijhuis 5, A. Wensing 5, , J. Schulze Zur Wiesch 1, A. Sáez-Cirión 2
1 Department of Medicine, Infectious Diseases Unit, University Medical Center Hamburg-Eppendorf – Hamburg (GER)
2 Institut Pasteur, HIV, Inflammation and Persistence – Paris (FRA)
3 AIDS Research Institute IrsiCaixa – Barcelona (SPA)
4 Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitarias Gregorio
Marañón, Universidad Complutense – Madrid (SPA)
5 University Medical Center – Utrecht (NET)
OP 4.6 : Dynamics of HIV-Specific T-Cells on Long-Term ART Differ by Antigen Recognized and by Sex
Author(s): Eva M. Stevenson1, Adam R. Ward 1,2,3, Thomas R. Dilling 1, John K. Bui 1, John Mellors 4, Rajesh Gandhi 5, Deborah McMahon 4, Joseph Eron 6, Ronald Bosch 7, Christina Lalama 7, Joshua Cyktor 4, and Brad Jones 1,2, for the A5321 Team
1 Division of Infectious Diseases, Weill Cornell Medicine, New York, NY (USA)
2 Department of Microbiology, Immunology, and Tropical Medicine, George Washington
University, Washington, DC (USA)
3 PhD program in Epidemiology, George Washington University, Washington, DC (USA)
4 University of Pittsburgh, Pittsburgh, PA (USA)
5 Massachusetts General Hospital, Boston, MA (USA)
6 University of North Carolina, Chapel Hill, NC (USA)
7 Harvard University, Boston, MA (USA)